A wave of technologies transformed sequencing over a decade ago into the high-throughput era, demanding research in new computational methods to analyze this data. The applications of sequencing have continually expanded. The Ninth RECOMB Satellite Workshop on Massively Parallel Sequencing (RECOMB-Seq) brings together leading researchers in computational genomics and genomic biology to discuss emerging frontiers in algorithm development for massively parallel sequencing data. The emphasis of all contributed work will be on applying statistical and algorithmic approaches to improve sequence data management, analysis, and interpretation.

Topics of Interest (including but not limited to)
  • Read mapping for second and third generation sequencing technologies
  • Techniques for managing (e.g., data compression) and visualizing massive amount of sequencing data
  • Consensus sequence construction
  • Discovery and genotyping of genomic variants, including SNPs, indels, and structural variants
  • Local and de novo sequence assembly
  • Methods for analysis of RNA sequencing (RNA-seq) data, including RNA expression, novel transcript assembly and splicing
  • Methods for novel sequencing technologies such as single-cell sequencing, linked-read sequencing and Hi-C
  • Translational applications of sequencing data, including cancer genomics and infectious disease
  • Epigenetics and gene regulation, including ChIP-seq analysis, methylation profiling, and histone modification
  • Metagenomics


We solicit contributions in four different categories as follows:

Proceedings track

This track solicits manuscripts describing original work on computational aspects of genomic research involving massively parallel sequencing. All manuscripts in this track will be considered for publication in a special issue of the journal iScience. At the time of submission, and for the entire review period, the work should not be under review by any other conference or scientific journal. Authors of manuscripts that are selected for oral presentation at RECOMB-seq after review but are not deemed suitable for iScience (or if the authors do not select publication in iScience) will be required to host their manuscript on a public preprint server.

Overlay track

Manuscripts submitted to this track will be reviewed by the program committee and selected submissions will be invited for oral presentation. The manuscript should be hosted on a public preprint server (bioRxiv, arXiv or PeerJ) at the time of submission. There are no specific formatting or page length requirements, but the paper should generally be formatted in a way that emphasizes the methodological contributions. Manuscripts can be submitted elsewhere at the same time but should not be published or in press at the time of submission.

Highlights Track

This track is for papers that have already been published or are in press. This track is joint with the main conference (deadline January 31 2019). For instructions and more details, see the RECOMB 2019 website

Abstracts for short talks or posters

Regular abstracts describing original work, including software applications. These will be considered for short oral presentations or posters. A 1-2 page abstract describing the methods and key results should be submitted via the EasyChair system.


All submissions to the proceedings track will be simultaneously considered for publication in a special issue of the journal iScience, if the authors agree. iScience is an open-access journal published by Cell Press for original research in the life, physical, and earth sciences. In addition to the program committee of RECOMB-seq, editors of iScience will evaluate the papers for biological impact and suitability for publication. Authors who do not wish their manuscript to be considered for iScience should use the overlay track for submission. Publication in iScience is subject to a publication charge of $3000.

Paper and abstract submission Procedures

Manuscripts for the ‘proceedings track’ should not exceed 10 pages using at least 11 point font on U.S. standard 8 1/2 by 11 inch paper with no less than one inch margin all around. This excludes the cover page and references. The cover page should have the title and the corresponding author’s email address. An optional short appendix, if absolutely necessary, can be included but will be considered at the discretion of the program committee. Manuscripts must be submitted electronically in PDF format via the EasyChair system.

The submission system will be open starting December 21st, 2018 and ending February 6th, 2019. It is required to submit an abstract for your paper before February 4th, 2019. Authors will be notified of acceptance or rejection by email on or before March 4th, 2019. An author of each accepted paper is expected to attend the workshop and present the paper; otherwise, alternative arrangements should be made to have the paper presented.

Special Handling of Papers Submitted to RECOMB 2019

If you would like to consider submitting a paper rejected by RECOMB 2019 to the workshop, you may do so by the regular deadline of February 6th, 2019. You must include in your submission a Cover Letter that includes the reviews received from RECOMB together with a rebuttal addressing the concerns raised by the reviewers. The submitted manuscript should also be modified according to the reviews, or provide an explanation of why modifications are unnecessary. All reviews will be treated confidentially and will only be visible to the PC members evaluating your paper.